Functional Magnetic Adsorption Material
admin
2022-09-12
功能化磁性吸附材料
Functional Magnetic Adsorption Material
技术编号
XN-095
提供单位
中国科学院过程工程研究所
技术大类
其他技术
联系人
任贝
技术类型
其他技术
电话
18813162152
邮箱
kaifa@ipe.cas.cn
适用范围
功能化磁性吸附材料
推荐单位
广西东盟技术转移中心
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技术简要说明该技术创制了一种制备磁性高分子微球的喷流悬浮聚合反应新工艺和反应装置,规模制备了聚苯乙烯、聚甲基丙烯酸甲酯、聚丙烯醇、聚甲基丙烯酸缩水甘油酯及二氧化硅、氧化铝等多种超顺磁性颗粒。在国际上率先实现了高吸附容量蛋白质亲和分离磁性颗粒、氨基硅烷偶联的SiO.磁性纳米颗粒等多种功能化超顺磁性颗粒的大规模制备。所获得的功能化磁性颗粒的吸附容量是市售产品的几倍到几十倍。创制了多种磁性分离/催化装置,包括用于蛋白质分离的超顺磁性颗粒连续化分离装置、流体中超细磁性颗粒的连续高效磁分离装置等等。实现了大流量液体中的超细磁性颗粒的有效分离和循环使用。获得2014年国家技术发明二等奖,成果已推广实施到多家合作企业,率先实现了超顺磁性颗粒的大规模制备及在蛋白质分离方面的工业化应用,解决了纳豆激酶的分离问题,降低了生产成本,提高了生产效率;发明的永磁分离装置用于工业催化生产中活性镍催化剂纳米颗粒的回收,实现了催化剂原位在线分离,分别应用于企业橡胶防老剂催化加氢,以及己内酰胺催化加氢等相关生产。 生物过程已从食品、医药拓展到能源、化工、冶金、环境等领域,成为可持续发展的产业之一。从生物质高值化利用、基因表达、蛋白质合成,到细胞生长和产物代谢,乃至生物治金、生物催化与生物基化学品,其过程强化与集成技术都很缺乏。
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Technical Brief DescriptionThis technology represents a new process and reaction device for jet suspension polymerization to manufacture magnetic polymer microspheres. We have manufactured multiple superparamagnetic particles such as polystyrene, polymethyl methacrylate, polyacrylic alcohol, polymethyl glycidyl acrylate, silica and alumina on a large scale. We are the first in the world to manufacture a variety of functional superparamagnetic particles such as high adsorption capacity protein affinity separation magnetic particles and amino silane coupled SiO magnetic nanoparticles on a large scale. The adsorption capacity of the functional magnetic particles we have obtained is several times to dozens of times that of the commercially available products. We have created multiple magnetic separation/catalysis devices, including the continuous separation device of superparamagnetic particles for protein separation, and the continuous high-efficiency magnetic separation device for ultrafine magnetic particles in fluids, thereby achieving the effective separation and recycling of ultrafine magnetic particles in large flow liquids. This technology was given the second prize of the National Technical Invention Award in 2014, and has been applied by multiple cooperative enterprises, for which we are the first to realize the large-scale manufacturing of superparamagnetic particles and its industrial application in protein separation. With this technology, we have solved the separation problem of nattokinase, reduced the production cost, improved the production efficiency. The permanent magnetic separation device we have invented is used for recovering active nickel catalyst nanoparticles in industrial catalytic production, realizing in-situ online separation of catalysts. It is also applied in the catalytic hydrogenation of rubber antioxidant and caprolactam by enterprises. Its biological process has expanded from food, medicine to energy, chemical industry, metallurgy, environment and other fields, for which it has become a sustainable industry. It still lacks process intensification and integrated technology in terms of high-value utilization of biomass, gene expression, protein synthesis, cell growth, product metabolism, biological metallurgy, biocatalysis and bio based chemicals.
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技术提供方中国科学院过程工程研究所
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